Acute Ischemic Stroke in Patients With COVID-19
| Autor: | Joseph H. Williams, Shuaiqi Zhang, Pratyaksh K Srivastava, Marquita Decker-Palmer, Gregg C. Fonarow, Mitchell S.V. Elkind, James A. de Lemos, Ying Xian, Jason G. Walchok, Steve R. Messe, Heather M. Alger, Brooke Alhanti, Hanzhang Xu, Christine Rutan, Eric E. Smith, Lee H. Schwamm |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Comorbidity 030204 cardiovascular system & hematology Brain Ischemia Time-to-Treatment 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Humans Medicine In patient Hospital Mortality Registries Acute ischemic stroke Stroke Aged Ischemic Stroke Retrospective Studies Aged 80 and over Advanced and Specialized Nursing business.industry COVID-19 Middle Aged medicine.disease Quality Improvement Hospitals Practice Guidelines as Topic Cardiology Female Neurology (clinical) Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery |
| Zdroj: | Stroke. 52:1826-1829 |
| ISSN: | 1524-4628 0039-2499 |
| Popis: | Background and Purpose: Studies suggest an increased risk of adverse outcomes among patients with acute ischemic stroke (AIS) and coronavirus disease 2019 (COVID-19). Methods: Using Get With The Guidelines–Stroke, we identified 41 971 patients (AIS/COVID-19: 1143; AIS/no COVID-19: 40 828) with AIS hospitalized between February 4, 2020 and June 29, 2020, from 458 Get With The Guidelines–Stroke hospitals with at least one COVID-19 case and evaluated clinical characteristics, treatment patterns, and outcomes. Results: Compared with patients with AIS/no COVID-19, those with AIS/COVID-19 were younger, more likely to be non-Hispanic Black, Hispanic, or Asian, more likely to present with higher National Institutes of Health Stroke Scale scores, and had greater proportions of large vessel occlusions. Rates of thrombolysis and thrombectomy were similar between the groups. Door to computed tomography (median 55 [18–207] versus 35 [14–99] minutes, P P P =0.002) times were longer in the AIS/COVID-19 cohort. In adjusted models, patients with AIS/COVID-19 had decreased odds of discharge with modified Rankin Scale score of ≤2 (odds ratio, 0.65 [95% CI, 0.52–0.81], P P ConclusionS: This analysis demonstrates younger age, greater stroke severity, longer times to evaluation and treatment, and worse morbidity and mortality in patients with AIS/COVID-19 compared with those with AIS/no COVID-19. |
| Databáze: | OpenAIRE |
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