Regio- and Stereoselective Photoredox-Catalyzed Atom Transfer Radical Addition of Thiosulfonates to Aryl Alkynes
| Autor: | Hui Zhang, Zhiyuan Peng, Haolin Yin, Tiezheng Jia |
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| Rok vydání: | 2020 |
| Předmět: |
010405 organic chemistry
Chemistry Atom-transfer radical-polymerization Aryl Organic Chemistry Regioselectivity 010402 general chemistry 01 natural sciences Biochemistry Combinatorial chemistry 0104 chemical sciences Catalysis chemistry.chemical_compound Stereoselectivity Physical and Theoretical Chemistry Thiyl radicals |
| Zdroj: | Organic Letters. 22:5885-5889 |
| ISSN: | 1523-7052 1523-7060 |
| Popis: | Despite extensive investigations, altering the regioselectivity of atom transfer radical addition (ATRA) to alkynes remains a highly desirable yet unachieved challenge. Guided by computational predictions, thiosulfonates were found herein as a tunable radical precursor for thiyl radicals instead of well-recognized sulfonyl radicals. Merging such a finding with ATRA to phenylacetylenes leads to a highly regio- and stereoselective approach to ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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