Practical application of electron microscopy to neuromuscular diseases

Autor:	Werner Stenzel, Hans H. Goebel
Rok vydání:	2013
Předmět:	Neurogenic atrophy Pathology medicine.medical_specialty Muscle Fibers Skeletal Anatomy Neuromuscular Diseases Biology Ultrastructural Pathology Pathology and Forensic Medicine law.invention Microscopy Electron Structural Biology law Predictive Value of Tests Reducing bodies Ultrastructure medicine Humans Electron microscope
Zdroj:	Ultrastructural pathology. 37(1)
ISSN:	1521-0758
Popis:	Concerning individual neuromuscular conditions, electron microscopy may be considered “essential,” “helpful,” or “wasteful.” “Essential” electron microscopy should provide a clear diagnosis, because of the disease specificity of the ultrastructural findings, in particular as to inclusions within muscle fibers, such as cylindrical spirals and reducing bodies. Electron microscopy may be “helpful” in detecting ultrastructural features preceding typical light microscopic findings, for instance, undulating tubules in endothelial cells. Congenital, metabolic, and inflammatory myopathies may often be more easily and more reliably diagnosed by means of the electron microscope. Diagnostically “wasteful” electron microscopy may pertain to muscular dystrophies, neurogenic atrophy, and myotonic diseases.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bdf7933c6d3de0dc21abf08b1eacc69 https://pubmed.ncbi.nlm.nih.gov/23383613 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.