An efficient synthesis of 6-arylbenzo[4,5]imidazo[2,1-a]isoquinolines via sequential α-arylation of carbonyl and deacylation catalyzed by CuI

Autor:	Xiang-Shan Wang, Wei-Qing Miao, Jian-Quan Liu
Rok vydání:	2017
Předmět:	Dibenzoyl methane Nucleophilic addition 010405 organic chemistry Chemistry Organic Chemistry Organic chemistry Physical and Theoretical Chemistry 010402 general chemistry 01 natural sciences Biochemistry 0104 chemical sciences Catalysis
Zdroj:	Organic & Biomolecular Chemistry. 15:5325-5331
ISSN:	1477-0539 1477-0520
Popis:	Dibenzoyl methane was found to undergo α-arylation of carbonyl and deacylation reaction with 2-(2-bromophenyl)-1H-benzo[d]imidazoles catalyzed by CuI in the presence of Cs2CO3, and provided an efficient synthesis of 6-arylbenzo[4,5]imidazo[2,1-a]isoquinolines.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bdefa0df119999ad74c5793fc8f196d https://doi.org/10.1039/c7ob01022b Zobrazit plný text záznamu