Large fetal size in early pregnancy associated with macrosomia
| Autor: | H. Almström, Ellika Andolf, Magnus Kaijser, Malin Thorsell |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Birth weight Early pregnancy factor Gestational Age Risk Assessment Fetal Macrosomia Fetal Development Pregnancy Risk Factors Odds Ratio Medicine Humans Radiology Nuclear Medicine and imaging Retrospective Studies Ultrasonography Gynecology Sweden Fetus Radiological and Ultrasound Technology biology business.industry Obstetrics Singleton Obstetrics and Gynecology Retrospective cohort study General Medicine Odds ratio Obstetric Labor Complications Risk Estimate Reproductive Medicine Pregnancy Trimester Second biology.protein Gestation Female business |
| Zdroj: | Ultrasound in obstetricsgynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology. 35(4) |
| ISSN: | 1469-0705 |
| Popis: | Objective To assess if fetal size at the time of ultrasound dating examination is associated with the risk of macrosomia and complications associated with macrosomia. Methods This was a retrospective cohort study of 19 377 singleton pregnancies dated in gestational weeks 16–20 during the period 1998–2004 at Danderyd Hospital, Stockholm, Sweden. Obstetric outcome was assessed through linkage to the Swedish Medical Birth Register. Results When fetuses were ≥ 7 days larger than expected at dating, compared with the expected size according to last menstrual period, there was a 59% increase in the risk of birth weight ≥ 4500 g and a 145% increase in the risk of birth weight ≥ 5000 g (odds ratio (OR), 1.59; 95% CI, 1.12–2.24 and OR, 2.45; 95% CI, 1.22–4.90, respectively). For a birth weight of ≥ 4000 g the risk estimate was 1.19 (95% CI, 0.96–1.47). Conclusion Fetuses that are larger than expected in the second trimester have an increased risk of macrosomia. This emphasizes that fetal size in early pregnancy is not only a function of gestational duration, but also of fetal growth. However, only a limited proportion of all infants born macrosomic can be identified as such at the time of ultrasound dating. Copyright © 2009 ISUOG. Published by John Wiley & Sons, Ltd. |
| Databáze: | OpenAIRE |
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