Effect of miconazole on growth and aflatoxin production by Aspergillus parasiticus
| Autor: | Heidi G. Stahl, Susan B. Jones, Robert L. Buchanan |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
Glycerol
Aflatoxin Miconazole Veterinary (miscellaneous) Mitochondrion Applied Microbiology and Biotechnology Microbiology chemistry.chemical_compound Oxygen Consumption Aflatoxins Biosynthesis medicine Mycotoxin Aspergillus biology Hydrogen-Ion Concentration biology.organism_classification Aspergillus parasiticus Culture Media Mitochondria Microscopy Electron chemistry Agronomy and Crop Science medicine.drug |
| Zdroj: | Mycopathologia. 100:135-144 |
| ISSN: | 1573-0832 0301-486X |
| DOI: | 10.1007/bf00437039 |
| Popis: | At 5 microM, miconazole prevented the growth of Aspergillus parasiticus Speare in a number of media. Sensitivity to miconazole was increased approximately 10-fold in a medium containing glycerol. At sub-inhibitory concentrations, miconazole stimulated aflatoxin synthesis on media which normally support toxin formation. Miconazole inhibited respiration and altered mitochondrial ultrastructure, suggesting that miconazole inhibits growth and stimulates aflatoxin production by depressing mitochondrial activity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink