Antidepressant efficacy and side effect burden: an updated guide for clinicians
| Autor: | Trevor Scudamore, Thomas L. Schwartz, Mark Wiener, Michelle Dick, Tatum Kutzer |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Postpartum depression
medicine.medical_specialty Side effect Review 03 medical and health sciences neuromodulator 0302 clinical medicine medicine Intensive care medicine Depression (differential diagnoses) Pharmacology chemistry.chemical_classification major depressive disorder business.industry lcsh:RM1-950 General Medicine medicine.disease 030227 psychiatry Review article antipsychotics therapeutic lcsh:Therapeutics. Pharmacology chemistry postpartum depression antidepressants depression treatment-resistant depression Molecular Medicine Major depressive disorder Antidepressant business Treatment-resistant depression 030217 neurology & neurosurgery Tricyclic |
| Zdroj: | Drugs in Context, Vol 9, Pp 1-11 (2020) Drugs in Context |
| ISSN: | 1740-4398 |
| Popis: | Antidepressant treatment has been evolving and changing since the 1950s following the discovery of the classic antidepressant treatments including tricyclic antidepressants and monoamine oxidase inhibitors. The heterogeneity of the disorder became apparent in the beginning when individuals remained symptomatic despite medication compliance. This spurred further research in order to understand the neurobiology underlying the disorder. Subsequently, newer medications were designed to target specific neurotransmitters and areas of the brain involved in symptom development and maintenance. Our original review article looked at both classic and modern antidepressant medications used in the treatment of major depressive disorder. This manuscript is an update to the original review and serves to provide clinicians with information about novel antidepressant medications, augmentation strategies with atypical antipsychotics, over-the-counter medications, as well as nonpharmaceutical treatments that should be considered when treating each individual patient who remains symptomatic despite treatment efforts. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|