Immunoglobulin A mediation of murine nasal anti-influenza virus immunity
| Autor: | Parker A. Small, K B Renegar |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Immunoglobulin A
viruses Immunology Orthomyxoviridae chemical and pharmacologic phenomena Virus Replication Microbiology Virus Mice Immune system Orthomyxoviridae Infections Immunity Virology Immune Tolerance Animals Antiserum Mice Inbred BALB C biology virus diseases biochemical phenomena metabolism and nutrition biology.organism_classification Immunity Innate Immunoglobulin M Insect Science biology.protein bacteria Female Nasal administration Nasal Cavity Antibody Research Article |
| Zdroj: | Journal of Virology. 65:2146-2148 |
| ISSN: | 1098-5514 0022-538X |
| DOI: | 10.1128/jvi.65.4.2146-2148.1991 |
| Popis: | Most mice which have recovered from influenza virus infection are immune to reinfection with the same influenza virus. This immunity could be abrogated by the intranasal instillation of anti-immunoglobulin A (anti-IgA) but not of anti-IgG or anti-IgM antiserum. Thus, IgA is the major, if not the sole, mediator of nasal immunity to influenza virus in immunocompetent mice. |
| Databáze: | OpenAIRE |
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