Human placental lactogen and pregnancy-associated plasma protein A in first trimester and subsequent fetal growth
Autor: | Steen Sørensen, Jan Fog Pedersen, Susanne Ruge |
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Rok vydání: | 1995 |
Předmět: |
medicine.medical_specialty
Pregnancy-associated plasma protein A Birth weight Gestational Age Embryonic and Fetal Development Human placental lactogen Pregnancy Internal medicine Blood plasma medicine Birth Weight Humans Pregnancy-Associated Plasma Protein-A Placental lactogen Fetus business.industry Infant Newborn Obstetrics and Gynecology Gestational age General Medicine Placental Lactogen Blood proteins Pregnancy Trimester First Endocrinology Female business |
Zdroj: | Acta Obstetricia et Gynecologica Scandinavica. 74:505-508 |
ISSN: | 1600-0412 0001-6349 |
DOI: | 10.3109/00016349509024379 |
Popis: | To study in an optimized design the possible relation between serum levels in weeks 8-14 of human placental lactogen and pregnancy-associated plasma protein A and fetal size at delivery.Analysis of data from 93 normal singleton pregnancies. Gestational age was assessed from a sonographic crown-rump length measurement. Serum levels of human placental lactogen and pregnancy-associated plasma protein A were determined by radioimmunoassay, and were expressed in multiples of mean. The relative birth weight was used as an index of fetal growth.Serum levels of human placental lactogen and pregnancy-associated plasma protein A showed a negative correlation to gestational age at delivery (p0.01 and p0.05, respectively), and there was a positive correlation between the serum level of pregnancy-associated plasma protein A and relative birth weight (p0.02).Higher levels of human placental lactogen and pregnancy-associated plasma protein A predicted earlier delivery, maybe because of better fetal growth, and higher levels of pregnancy-associated plasma protein A predicted better fetal growth. |
Databáze: | OpenAIRE |
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