Effect of NO-synthase inhibitor L-NAME on occlusion and reperfusion arrhythmias in cats
| Autor: | L. A. Balykova, A. A. Sosunov, L. K. Fedotkina, V. P. Balashov, O. I. Kukushkina |
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| Předmět: |
medicine.medical_specialty
Reperfusion arrhythmias CATS business.industry General Medicine medicine.disease General Biochemistry Genetics and Molecular Biology Nitric oxide chemistry.chemical_compound medicine.anatomical_structure chemistry Internal medicine Anesthesia No synthase Ventricular fibrillation Occlusion cardiovascular system medicine Cardiology cardiovascular diseases Ligation business Artery |
| Zdroj: | Scopus-Elsevier |
| Popis: | On the model of occlusion/reperfusion arrhythmia in cats it was shown that repeated injections of the NO-synthase inhibitor L-NAME decreased the incidence of occlusion arrhythmias (to 40%), eliminated reperfusion-induced ventricular fibrillation, and drastically reduced the latency of occlusion arrhythmias. A single injection of L-NAME (20 mg/kg) immediately before ligation of the coronary artery did not decrease the incidence of occlusion and reperfusion arrhythmias. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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