Therapeutic effect of indirubin-loaded bovine serum albumin nanoparticules on ulcerative colitis

Autor:	Guang-Min Yu, Li-Feng Zhou, Xiao-Ming Liu, Bin Liu, Xue-Ying Lai, Chu-Lan Xu, Ming-Yi Long, Yan-Ming Zhu, Ji-De Wang, Ming-Song Li
Rok vydání:	2022
Předmět:	Disease Models Animal Mice Mice Inbred BALB C Indoles Dextran Sulfate Biomedical Engineering Animals Humans Colitis Ulcerative Serum Albumin Bovine General Materials Science
Zdroj:	Biomaterials Science. 10:2215-2223
ISSN:	2047-4849 2047-4830
Popis:	Indirubin is considered to have promising potential in the treatment of ulcerative colitis (UC). However, poor aqueous solubility and low bioavailability limit its clinical application. We produced indirubin-loaded bovine serum albumin nanoparticles (INPs) and characterized their drug encapsulation efficiency, drug-loading capacity, capacity to release indirubin
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba40fd529a59e9516463614a2716d4a https://doi.org/10.1039/d1bm01896e Zobrazit plný text záznamu