CHEMICAL ANALYSES OF TWO PATHOLOGICAL HUMAN BRAINS

Autor:	C. G. MacARTHUR, E. A. Doisy
Rok vydání:	1919
Předmět:	Pathology medicine.medical_specialty Cerebrum Chemistry Bulbar paralysis Pons Brain disease Midbrain Psychiatry and Mental health medicine.anatomical_structure medicine sense organs medicine.symptom skin and connective tissue diseases Pathological Medulla Paresis
Zdroj:	American Journal of Psychiatry. 76:159-167
ISSN:	1535-7228 0002-953X
DOI:	10.1176/ajp.76.2.159
Popis:	The principal changes in the cerebrum of the case of paresis ("Path. K.") were in the lipins and extractives. The substances (cerebrosides) associated most closely with sheath development showed largest losses. The phosphatids and sulphatids are present in smaller amounts than in normal cerebra. Both organic and inorganic extractives show maked increases in percentage and absolute amounts. This is to be expected in degenerative changes, if it is the more complex structure substances that alter to simpler compounds which are but partly removed from the tissue. The changes in the cerebrum in the case of organic brain disease ("Path. A.") (probably bulbar paralysis) which gave a syphilitic history show essentially the same kind of change as the case above; but all were less marked. This would suggest that the alterations were due to the action of spirochaetes. The midbrain, medulla, and pons exhibited about the same kind of chemical changes as the cerebrum. The cerebrosides, sulphatids and phosphatids, and th...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba10c2a9c0b791cd2192f3fb07d3365 https://doi.org/10.1176/ajp.76.2.159 Zobrazit plný text záznamu