Clinical characteristics and treatment outcomes of tuberculosis in theelderly: a case control study
| Autor: | In-Jae Oh, Kyu Sik Kim, Sung Chul Lim, Young-Chul Kim, Yong Soo Kwon, Su Young Chi, Yu Il Kim |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty Tuberculosis Antitubercular Agents Drug resistance Medical microbiology Age Clinical presentations Diagnosis Treatment outcome Internal medicine Drug Resistance Bacterial Republic of Korea medicine Humans Aged Retrospective Studies business.industry Incidence (epidemiology) Medical record Case-control study Age Factors Retrospective cohort study Middle Aged medicine.disease Surgery Infectious Diseases Treatment Outcome Case-Control Studies Female business Adverse drug reaction Research Article |
| Zdroj: | BMC INFECTIOUS DISEASES(13) BMC Infectious Diseases |
| Popis: | Background: The purpose of this study was to evaluate the differences in clinical characteristics and treatment outcomes between older and younger tuberculosis (TB) patients in Korea. Methods: We retrospectively analyzed the medical records of 271 younger (20-64 years old at diagnosis) and 199 older (>= 65 years) TB patients who had been newly diagnosed and treated at Chonnam National University Hospital from May 2008 to August 2010. Results: Dyspnea and comorbid medical conditions were more frequent and positive TB culture rates were higher in older TB patients. In chest computed tomography (CT) scans of pulmonary TB patients, older patients were less likely to have micronodules (30 mm in diameter), and cavities compared with younger patients, but were more likely to have consolidations. Incidence of adverse drug reactions did not differ between the two groups, except for severe gastrointestinal disorders. There were no significant differences in favorable treatment outcomes between younger and older TB patients (97% vs. 94%, respectively; p = 0.251). Conclusions: Older TB patients had more frequent dyspnea and less frequent active TB findings on chest CT. Treatment success and adverse drug reaction rates were similar in older and younger TB patients. |
| Databáze: | OpenAIRE |
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