Additional file 4: of Systematic characterization of germline variants from the DiscovEHR study endometrial carcinoma population

Autor: Miller, Jason, Raghu Metpally, Person, Thomas, Sarathbabu Krishnamurthy, Venkata Dasari, Shivakumar, Manu, Lavage, Daniel, Cook, Adam, Carey, David, Ritchie, Marylyn, Dokyoon Kim, Gogoi, Radhika
Rok vydání: 2019
Předmět:
DOI: 10.6084/m9.figshare.8080421
Popis: Figure S4. pLoF variants among OHRM and NCC cohorts. For each gene with two variants in both cohorts, the ratio of non-synonymous variants across the OHRM cohort was divided by those in the NCC after adjusting for differences in cohort size. Orange, blue and red lines are used to delineate 2, 1 and 0.5 fold EMCA burden relative to the NCC cohort. The graph inset represents the raw number of variants at each gene between the OHRM and NCC cohort. (B) The number of rare pLoF variants from each cohort. (PPTX 73879 kb)
Databáze: OpenAIRE