Anodically Triggered Aldehyde Cation Autocatalysis for Alkylation of Heteroarenes
| Autor: | Shuhua Wu, Yongli Shen, Caiyan Liu, Zihui Xiao, Yi Ding, Kedong Yuan |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
chemistry.chemical_classification
General Chemical Engineering Cationic polymerization Regioselectivity 02 engineering and technology Alkylation 010402 general chemistry 021001 nanoscience & nanotechnology Electrochemistry Electrosynthesis 01 natural sciences Aldehyde Combinatorial chemistry 0104 chemical sciences Autocatalysis General Energy chemistry Environmental Chemistry General Materials Science 0210 nano-technology Stoichiometry |
| Zdroj: | ChemSusChem. 13:1997-2001 |
| ISSN: | 1864-564X 1864-5631 |
| DOI: | 10.1002/cssc.201903397 |
| Popis: | Alkylation of heteroarenes by using aldehydes is a direct approach to increase molecular complexity, which however often involves the use of stochiometric oxidant, strong acid, and high temperature. This study concerns an energy-efficient electrochemical alkylation of heteroarenes by using aldehydes under mild conditions without mediators. Interestingly, the graphite anode can trigger aldehyde cationic species, which act as the effective autocatalysts to react with a range of heteroarenes to produce the corresponding products with excellent regioselectivity and in high yields. Compared to the traditional electro-synthesis approaches, this electro-triggered reaction provides an electricity-saving and eco-friendly route to high-value chemicals. |
| Databáze: | OpenAIRE |
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