Failure of intravenous antibiotic therapy of multiple temporal brain abscesses due to Propionibacterium acnes requiring temporal lobectomy
| Autor: | O. Lamy, L. Dubreuil, Yves Mouton, F. Ajana, C. Savage, A. Fawaz, Christian Chidiac, J.M. Bourez, Eric Senneville |
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| Rok vydání: | 1997 |
| Předmět: |
Adult
Male Microbiology (medical) medicine.medical_specialty medicine.drug_class medicine.medical_treatment Antibiotics Brain Abscess Temporal lobe Propionibacterium acnes Humans Medicine Abscess Gram-Positive Bacterial Infections Antibacterial agent Chemotherapy biology business.industry biology.organism_classification medicine.disease Temporal Lobe Anti-Bacterial Agents Surgery Penicillin Infectious Diseases business Complication medicine.drug |
| Zdroj: | Journal of Infection. 34:269-271 |
| ISSN: | 0163-4453 |
| DOI: | 10.1016/s0163-4453(97)94479-0 |
| Popis: | Propionibacterium acnes is a common skin colonizer. Its involvement in brain abscesses is generally described as a complication of neurosurgical intervention. Propionibacterium acnes is susceptible to antibiotics used as treatment of anaerobic infections, except for the 5-nitroimidazoles. Surgical excision or drainage of a simple abscess combined with a long course of antibiotics is considered the treatment of choice. A case of a patient with multiple brain abscesses located in the right temporal lobe that occurred after the manipulation of an abscess of the right upper maxillary is reported. The patient did not improve despite a prolonged course of high-dose intravenous penicillin plus thiamphenicol, and cure was finally obtained after the excision of the right temporal lobe. Culture of the purulent material and the shell of the abscesses yielded P. acnes which was sensitive to all the antibiotics administered to the patient up to the intervention. The temporal lobectomy was followed by a 6-month course of ofloxacin. One year after the intervention, the patient remained apyretic without any other abscess on cranial computed tomography scan. |
| Databáze: | OpenAIRE |
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