Methods for diagnosing the risk factors of stone formation
Autor: | William G. Robertson |
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Jazyk: | angličtina |
Rok vydání: | 2012 |
Předmět: |
medicine.medical_specialty
RSS relative supersaturation genetic structures Urology Review Bioinformatics CP crystallisation potential NAE net acid excretion UA - Uric acid medicine Magnesium ammonium phosphate MAP magnesium ammonium phosphate Kidney stone Intensive care medicine Robertson Risk Factor Algorithms Stone formation business.industry BONN-Risk Index Bonn risk index medicine.disease CaP calcium phosphate CaOx calcium oxalate UA uric acid Tiselius Indices Kidney stones RRFA Robertson Risk Factor Algorithms business PSF overall biochemical risk of forming stones PRAL potential renal acid load Relative supersaturation |
Zdroj: | Arab Journal of Urology |
ISSN: | 2090-5998 2090-598X |
Popis: | Objective To compare various systems for assessing the risk of recurrent stones, based on the composition of urine. Methods The relative supersaturation (RSS) of urine, the Tiselius Indices, the Robertson Risk Factor Algorithms (RRFA) and the BONN-Risk Index were compared in terms of the numbers of variables required to be measured, the ease of use of the system and the value of the information obtained. Results The RSS methods require up to 14 analyses in every urine sample but measure the RSS of all the main constituents of kidney stones. The Tiselius Indices and the RRFA require only seven analyses. The Tiselius Indices yield information on the crystallisation potentials (CP) of calcium oxalate and calcium phosphate; the RRFA also provide information on the CP of uric acid. Both methods provide details on the particular urinary abnormalities that lead to the abnormal CP of that urine. The BONN-Risk Index requires two measurements in each urine sample but only provides information on the CP of calcium oxalate. Additional measurements in urine have to be made to identify the cause of any abnormality. Conclusions The methods that are based on measuring RSS are work-intensive and unsuitable for the routine screening of patients. The Tiselius Indices and the RRFA are equally good at predicting the risk of a patient forming further stones. The BONN-Risk Index provides no additional information about the causative factors for any abnormality detected. |
Databáze: | OpenAIRE |
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