B-cells of the synovial membrane. II. Differentiation during development of the synovial cavity in the mouse
| Autor: | Gabrielle Linck, Porte A |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Synovial cavity
Metatarsophalangeal Joint Pathology medicine.medical_specialty Histology Mesenchyme Mesenchymal stem cell Synovial Membrane Cell Differentiation Cell Biology Toe Joint Biology Chondrogenesis Cytoplasmic Granules Molecular medicine Secretory Vesicle Pathology and Forensic Medicine Mice medicine.anatomical_structure medicine Synovial fluid Animals Synovial membrane |
| Zdroj: | Cell and tissue research. 195(2) |
| ISSN: | 0302-766X |
| Popis: | Study of pre- and postnatal development of the metatarsophalangeal joint of the mouse shows that the synovial cavity (SC) forms before any differentiation of the synovial mesenchyme. The primitive cleft results from degradation of a thin vascular mesenchymal layer in direct contact with the chondrogenic layers. Differentiation of the synovial membrane coincides with clarification of the SC (3rd to 6th day of postnatal life). When dilatation of the SC occurs (6th to 8th day), the two intimal cells types (A- and B-cells) are well identified. The B-cells already show typical features at day 6; their content of typical dense secretory vesicles is comparable to that of the adult B-cells at day 13. The specific secretory function of B-cells could be correlated with the particular structure of the intimal interstitial tissue and could account for the origin of some protein(s) of the synovial fluid. |
| Databáze: | OpenAIRE |
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