Helicobacter pylori and childhood recurrent abdominal pain: community based case-control study
Autor: | Philip M. Sherman, Paul B. Pencharz, Colin Macarthur, Patricia Winders-Lee, William Feldman, Susan B. Roberts, L. Best, Norman R. Saunders, Sander Veldhuyzen van Zanten, Moshe Ipp |
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Rok vydání: | 1999 |
Předmět: |
Male
medicine.medical_specialty Abdominal pain Adolescent Disease Organic disease Helicobacter Infections Recurrence Internal medicine Epidemiology medicine Humans Child General Environmental Science biology Helicobacter pylori business.industry General Engineering Case-control study General Medicine biology.organism_classification Surgery Abdominal Pain medicine.anatomical_structure El Niño Case-Control Studies Child Preschool Papers General Earth and Planetary Sciences Abdomen Female medicine.symptom business |
Zdroj: | Scopus-Elsevier |
ISSN: | 0959-8138 |
Popis: | Recurrent abdominal pain (at least three discrete episodes of abdominal pain over a period of three or more months, and of sufficient severity to interrupt normal activities) is a common childhood complaint. We set out to determine the association, if any, between Helicobacter pylori infection and childhood recurrent abdominal pain. Cases and controls were drawn consecutively from the practice populations of six primary care paediatricians in Toronto. (Convenience sampling was used to select paediatricians; they were chosen because of their interest in the study.) Cases were children aged 5-15 years presenting with recurrent abdominal pain; controls were healthy children undergoing a routine check-up or vaccination. Excluded were children with concurrent disease, suspected organic disease, aged under five years, or who had used bismuth in the previous month. All families approached consented to participate. Serum IgG antibodies to H pylori were measured by using a flow microsphere immunofluorescent assay (FMIA) and a commercial immunoassay kit (Bio-Rad Laboratories, Hercules, CA). The FMIA method has been validated in children (100% sensitivity, 97% specificity) against … |
Databáze: | OpenAIRE |
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