Hepatitis A-Induced Diabetes Mellitus, Acute Renal Failure, and Liver Failure

Autor: Frederick F. Paustian, David L. Vesely, William C. Duckworth, Roger W. Dilley
Rok vydání: 1999
Předmět:
Zdroj: The American Journal of the Medical Sciences. 317:419-424
ISSN: 0002-9629
DOI: 10.1016/s0002-9629(15)40557-9
Popis: 38-year-old otherwise healthy man presented with hepatic failure (aspartate aminotransferase of 7212 U/L, alanine aminotransferase of 6629 U/L, total and direct bilirubin of 10.7 mg/dL) and acute renal failure (ereatinine of 11.6 mg/dL and blood urea nitrogen of 42 mg/dL), which required hemodialysis when the creatinine increased to 21 mg/dL, with a blood urea nitrogen of 115 mg/dL, and the patient became oliguric. On admission, this patient also had a lipase of 1833 U/L, amylase of 211 U/L, glucose of 210 mg/dL, and reactive IgM antibody for acute hepatitis A. The hepatitis and acute renal failure resolved in 3 months, but this patient continues to have type II diabetes mellitus 7 years after the hepatitis A infection. This case illustrates that hepatitis A infection may be severe with liver failure, acute renal failure, and permanent diabetes mellitus as sequale of this infection.
Databáze: OpenAIRE