Distinct subcortical tau burden: The tau pallido-claustral ratio separates progressive supranuclear palsy and corticobasal degeneration
| Autor: | Wenqing He, Chelsey ShengQi Zhao, Lei Yan, Qi Zhang, Lee Cyn Ang |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
business.industry
General Neuroscience Brain tau Proteins medicine.disease digestive system digestive system diseases eye diseases Pathology and Forensic Medicine Progressive supranuclear palsy Corticobasal Degeneration surgical procedures operative mental disorders Medicine Corticobasal degeneration Humans Neurology (clinical) Tauopathy Supranuclear Palsy Progressive business Neuroscience |
| Zdroj: | Brain pathology (Zurich, Switzerland). 32(2) |
| ISSN: | 1750-3639 |
| Popis: | Neuropathological diagnosis of progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) requires interpretation of tau morphology based on extensive brain sampling. Here we report subcortical tau burden is sufficient to distinguish PSP and CBD, regardless of the tau morphology. The tau pallido-claustral ratio is a promising diagnostic indicator for PSP and CBD. |
| Databáze: | OpenAIRE |
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