Interstitial granulomatous lesions as part of the spectrum of presenting cutaneous signs in pediatric sarcoidosis
| Autor: | Frank Pessler, Rosalie Elenitsas, Chad M. Hivnor, Dan Albert, Bruce Pawel, Brian Forbes, Albert C. Yan, Eun J. Kwon, Paul Honig |
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| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Pathology Systemic disease Sarcoidosis Biopsy Dermatology Skin Diseases Diagnosis Differential Granuloma Annulare hemic and lymphatic diseases medicine Humans Child Granuloma annulare Skin Interstitial granulomatous dermatitis business.industry medicine.disease Pediatrics Perinatology and Child Health Eyelid Diseases Histopathology Female Differential diagnosis business Granulomatous Dermatitis Epithelioid cell |
| Zdroj: | Pediatric dermatology. 24(5) |
| ISSN: | 1525-1470 |
| Popis: | Skin findings in childhood sarcoidosis vary greatly, but only a few occurrences have been published in which the histopathology has been characterized well. We describe a child with sarcoidosis in whom the cutaneous findings were atypical, resembling granuloma annulare. Histologic examination of these cutaneous lesions, however, revealed areas of sarcoid-like epithelioid cell granulomas, a palisading granulomatous process with features of granuloma annulare, as well as palisading neutrophilic and granulomatous dermatitis and interstitial granulomatous dermatitis. This underscores the variability of skin findings in childhood sarcoidosis--even within the same patient--and suggests that sarcoidosis should be considered in the differential diagnosis of children initially diagnosed with granulomatous skin lesions, such as granuloma annulare, palisading neutrophilic, and granulomatous dermatitis or interstitial granulomatous dermatitis, who demonstrate associated signs of systemic disease. |
| Databáze: | OpenAIRE |
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