Systematic review finds that appraisal tools for medical research studies address conflicts of interest superficially

Autor: Kristine Rasmussen, Lesley A. Stewart, Asbjørn Hróbjartsson, Lasse Østengaard, Andreas Lundh, Isabelle Boutron
Přispěvatelé: Centre for Evidence-Based Medicine Odense (CEBMO), Odense University Hospital (OUH), Open Patient data Exploratory Network (OPEN), Department of Clinical Research, University of Southern Denmark (SDU), Department of Infectious Diseases, Hvidovre Hospital, Cochrane Nordic, Rigshospitalet [Copenhagen], Copenhagen University Hospital-Copenhagen University Hospital, University Library of Southern Denmark, Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre for Reviews and Dissemination, University of York [York, UK]
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Lundh, A, Rasmussen, K, Østengaard, L, Boutron, I, Stewart, L A & Hrõbjartsson, A 2020, ' Systematic review finds that appraisal tools for medical research studies address conflicts of interest superficially ', Journal of Clinical Epidemiology, vol. 120, pp. 104-115 . https://doi.org/10.1016/j.jclinepi.2019.12.005
Journal of Clinical Epidemiology
Journal of Clinical Epidemiology, Elsevier, 2020, 120, pp.104-115. ⟨10.1016/j.jclinepi.2019.12.005⟩
ISSN: 0895-4356
DOI: 10.1016/j.jclinepi.2019.12.005
Popis: ObjectivesThe objective of this study was to identify and summarize 1) appraisal tools and other guides which address conflicts of interest in medical research studies; and 2) top journals with policies on managing conflicts of interest in journal papers.Study Design and SettingWe searched bibliographic databases, other sources, and websites of 30 top medical journals. Two authors selected documents and extracted data.ResultsWe included 27 appraisal tools. None were designed specifically for addressing conflicts of interest and they included only 1-2 short items on conflicts of interest. We also included eight other types of guides. Of 27 appraisal tools, 23 addressed study funding, and 19 authors’ conflicts of interest. Nine tools addressed availability of conflicts of interest information, 13 reported conflicts of interest, and five influence from conflicts of interest. Twelve of 30 top journals had conflicts of interest managing policies (beyond disclosure). One journal restricted nonresearch papers (e.g., editorials) to authors without financial conflicts of interest and ten only restricted under certain circumstances.ConclusionAppraisal tools that address conflicts of interest typically do so superficially and rarely address how conflicts of interest may influence studies. Less than half of top medical journals have explicit policies on managing conflicts of interest. ObjectivesThe objective of this study was to identify and summarize 1) appraisal tools and other guides which address conflicts of interest in medical research studies; and 2) top journals with policies on managing conflicts of interest in journal papers.Study Design and SettingWe searched bibliographic databases, other sources, and websites of 30 top medical journals. Two authors selected documents and extracted data.ResultsWe included 27 appraisal tools. None were designed specifically for addressing conflicts of interest and they included only 1-2 short items on conflicts of interest. We also included eight other types of guides. Of 27 appraisal tools, 23 addressed study funding, and 19 authors’ conflicts of interest. Nine tools addressed availability of conflicts of interest information, 13 reported conflicts of interest, and five influence from conflicts of interest. Twelve of 30 top journals had conflicts of interest managing policies (beyond disclosure). One journal restricted nonresearch papers (e.g., editorials) to authors without financial conflicts of interest and ten only restricted under certain circumstances.ConclusionAppraisal tools that address conflicts of interest typically do so superficially and rarely address how conflicts of interest may influence studies. Less than half of top medical journals have explicit policies on managing conflicts of interest.
Databáze: OpenAIRE
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