Capillary leak syndrome in neuromyelitis optica treated with rituximab
| Autor: | Rocío Hernández-Clares, Ester Carreon Guarnizo, Jose Meca Lallana, Ignacio Fuentes Fernandez |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Gastroenterology Anasarca Diagnosis Differential 03 medical and health sciences Fatal Outcome 0302 clinical medicine Internal medicine medicine Humans Immunologic Factors Neuromyelitis optica business.industry Multiple sclerosis Neuromyelitis Optica 030208 emergency & critical care medicine General Medicine Middle Aged medicine.disease Hemoconcentration Neurology Shock (circulatory) Immunology Female Rituximab Neurology (clinical) Differential diagnosis medicine.symptom business Capillary Leak Syndrome 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Multiple Sclerosis and Related Disorders. 16:22-23 |
| ISSN: | 2211-0348 |
| Popis: | 61-year-old woman with Neuromyelitis optica (NMO) diagnosis treated with rituximab was referred to our hospital with severe hypovolemic shock and anasarca. The laboratory findings showed marked hemoconcentration and a decrease in total serum protein. She developed a multiple organ failure and died three hours later. We diagnosed the patient as having capillary leak syndrome (CLS). CLS is a very rare condition caused by unexplained episodic capillary hyperpermeability, which can be idiopathic or secondary to some conditions like infection, malignant disease and some drugs like monoclonal antibodies. We reported the first CLS case in NMO patient treated with rituximab. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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