Asymmetric Ruthenium Catalysis Enables Fluorophores with Point Chirality Displaying CPL Properties

Autor: Yang Sun, Kais Dhbaibi, Hortense Lauwick, Claudia Lalli, Gregory Taupier, Yann Molard, Rafael Gramage‐Doria, Sylvie Dérien, Jeanne Crassous, Mathieu Achard
Přispěvatelé: Institut des Sciences Chimiques de Rennes (ISCR), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), We thank the Centre National de la Recherche Scientifique (CNRS) and the University of Rennes., Part of this work has been performed using the PRISM core facility (Biogenouest©, UMS Biosit, Université de Rennes 1 -Campus de Villejean, 35043 RENNES Cedex, FRANCE). The author thank T. Roisnel for X-ray diffraction analysis.
Rok vydání: 2022
Předmět:
Zdroj: Chemistry-A European Journal
Chemistry-A European Journal, 2023, 29 (10), ⟨10.1002/chem.202203243⟩
ISSN: 1521-3765
0947-6539
DOI: 10.1002/chem.202203243⟩
Popis: International audience; A novel enantiopure π-allylruthenium(IV) precatalyst allowed the enantioselective and stereospecific allylations of indoles and gave access to indolin-3-ones containing vicinal stereogenic centers. Facile separation of diastereoisomers exhibiting opposite CPL activities in diverse solvents including water demonstrated the potential of these sustainable transformation and of the newly prepared molecules.
Databáze: OpenAIRE
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