Tuberous Sclerosis Health Care Utilization Based on the National Inpatient Sample Database: A Review of 5655 Hospitalizations
| Autor: | Nitin Agarwal, Orrin Devinsky, Shaun D. Rodgers, David H. Harter, Michael M. McDowell, Taylor A. Wilson, Omar Tanweer, Howard L. Weiner, Bryan A. Lieber, Prateek Agarwal |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male congenital hereditary and neonatal diseases and abnormalities Adolescent medicine.medical_treatment Nervous System Neoplasms Population computer.software_genre Young Adult 03 medical and health sciences Tuberous sclerosis 0302 clinical medicine Tuberous Sclerosis Outcome Assessment Health Care Health care medicine Humans 030212 general & internal medicine Young adult Child education Craniotomy Retrospective Studies education.field_of_study Epilepsy Database business.industry Incidence (epidemiology) Infant Retrospective cohort study Patient Acceptance of Health Care medicine.disease nervous system diseases Hydrocephalus Hospitalization Child Preschool Female Surgery Neurology (clinical) business computer 030217 neurology & neurosurgery |
| Zdroj: | World Neurosurgery. 91:97-105 |
| ISSN: | 1878-8750 |
| DOI: | 10.1016/j.wneu.2016.03.043 |
| Popis: | Tuberous sclerosis complex (TSC) has an incidence of 1/6000 in the general population. Overall care may be complex and costly. We examine trends in health care utilization and outcomes of patients with TSC over the last decade.The National Inpatient Sample (NIS) database for inpatient hospitalizations was searched for admission of patients with TSC.During 2000-2010, the NIS recorded 5655 patients with TSC. Most patients were admitted to teaching hospitals (71.7%). Over time, the percentage of craniotomies performed per year remained stable (P = 0.351). Relevant diagnoses included neuro-oncologic disease (5.4%), hydrocephalus (6.5%), and epilepsy (41.2%). Hydrocephalus significantly increased length of stay and hospital charges. A higher percentage of patients who underwent craniotomy had hydrocephalus (29.8% vs. 5.3%; P0.001), neuro-oncologic disease (43.5% vs. 3.4%; P 0.001), other cranial diseases (4.2% vs. 1.2%; P0.001), and epilepsy (61.4% vs. 40.1%; P0.001).Our study identifies aspects of inpatient health care utilization, outcomes, and cost of a large number of patients with TSC. These aspects include related diagnoses and procedures that contribute to longer length of stay, increased hospital cost, and increased in-hospital mortality, which can inform strategies to reduce costs and improve care of patients with TSC. |
| Databáze: | OpenAIRE |
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