DNA polymerase I modulates inducible stable DNA replication in Escherichia coli
Autor: | Stuart Linn, T Ruscitti |
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Rok vydání: | 1992 |
Předmět: |
DNA Replication
DNA polymerase II DNA replication Eukaryotic DNA replication Biology DNA Polymerase I Microbiology Molecular biology DNA polymerase delta Replication factor C Control of chromosome duplication Escherichia coli biology.protein bacteria Origin recognition complex DNA polymerase I SOS Response Genetics Molecular Biology Research Article |
Zdroj: | Journal of Bacteriology. 174:6311-6313 |
ISSN: | 1098-5530 0021-9193 |
DOI: | 10.1128/jb.174.19.6311-6313.1992 |
Popis: | Mutants of Escherichia coli lacking RNase HI activity and cells induced for the SOS response express modes of DNA replication independent of protein synthesis, called constitutive and induced stable DNA replication, respectively. We report here that mutants deleted for the polA gene express induced stable DNA replication at approximately 25-fold the rate of wild-type cells, whereas constitutive stable DNA replication is not enhanced. |
Databáze: | OpenAIRE |
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