CT-derived 3D-diaphragm motion in emphysema and IPF compared to normal subjects

Autor: Chang Hoon Lee, Jiwoong Choi, Ching-Long Lin, Ji Hee Kang, Kyung Min Shin, Eric A. Hoffman, Junfeng Guo, Kum Ju Chae, Chang Hyun Lee
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Adult
Male
0301 basic medicine
medicine.medical_specialty
Science
Diaphragmatic breathing
Article
Young Adult
Computational biophysics
03 medical and health sciences
Basal (phylogenetics)
Idiopathic pulmonary fibrosis
Imaging
Three-Dimensional
0302 clinical medicine
Internal medicine
medicine
Humans
Displacement (orthopedic surgery)
Lung volumes
Expiration
Lung
Aged
Aged
80 and over
Respiratory tract diseases
Multidisciplinary
business.industry
Middle Aged
respiratory system
medicine.disease
Healthy Volunteers
Idiopathic Pulmonary Fibrosis
Diaphragm (structural system)
respiratory tract diseases
030104 developmental biology
medicine.anatomical_structure
Pulmonary Emphysema
030228 respiratory system
Cardiology
Medicine
Female
Lung Volume Measurements
Tomography
X-Ray Computed
business
Biological physics
Zdroj: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
ISSN: 2045-2322
Popis: Image registration-based local displacement analysis enables evaluation of respiratory motion between two computed tomography-captured lung volumes. The objective of this study was to compare diaphragm movement among emphysema, idiopathic pulmonary fibrosis (IPF) and normal subjects. 29 normal, 50 emphysema, and 51 IPF subjects were included. A mass preserving image registration technique was used to compute displacement vectors of local lung regions at an acinar scale. Movement of the diaphragm was assumed to be equivalent to movement of the basal lung within 5 mm from the diaphragm. Magnitudes and directions of displacement vectors were compared between the groups. Three-dimensional (3D) and apico-basal displacements were smaller in emphysema than normal subjects (P = 0.003, P = 0.002). Low lung attenuation area on expiration scan showed significant correlations with decreased 3D and apico-basal displacements (r = − 0.546, P P P P
Databáze: OpenAIRE
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