CT-derived 3D-diaphragm motion in emphysema and IPF compared to normal subjects
Autor: | Chang Hoon Lee, Jiwoong Choi, Ching-Long Lin, Ji Hee Kang, Kyung Min Shin, Eric A. Hoffman, Junfeng Guo, Kum Ju Chae, Chang Hyun Lee |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Science Diaphragmatic breathing Article Young Adult Computational biophysics 03 medical and health sciences Basal (phylogenetics) Idiopathic pulmonary fibrosis Imaging Three-Dimensional 0302 clinical medicine Internal medicine medicine Humans Displacement (orthopedic surgery) Lung volumes Expiration Lung Aged Aged 80 and over Respiratory tract diseases Multidisciplinary business.industry Middle Aged respiratory system medicine.disease Healthy Volunteers Idiopathic Pulmonary Fibrosis Diaphragm (structural system) respiratory tract diseases 030104 developmental biology medicine.anatomical_structure Pulmonary Emphysema 030228 respiratory system Cardiology Medicine Female Lung Volume Measurements Tomography X-Ray Computed business Biological physics |
Zdroj: | Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021) Scientific Reports |
ISSN: | 2045-2322 |
Popis: | Image registration-based local displacement analysis enables evaluation of respiratory motion between two computed tomography-captured lung volumes. The objective of this study was to compare diaphragm movement among emphysema, idiopathic pulmonary fibrosis (IPF) and normal subjects. 29 normal, 50 emphysema, and 51 IPF subjects were included. A mass preserving image registration technique was used to compute displacement vectors of local lung regions at an acinar scale. Movement of the diaphragm was assumed to be equivalent to movement of the basal lung within 5 mm from the diaphragm. Magnitudes and directions of displacement vectors were compared between the groups. Three-dimensional (3D) and apico-basal displacements were smaller in emphysema than normal subjects (P = 0.003, P = 0.002). Low lung attenuation area on expiration scan showed significant correlations with decreased 3D and apico-basal displacements (r = − 0.546, P P P P |
Databáze: | OpenAIRE |
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