Effect of Nutritional Supplements on Immune Function and Body Weight in Malnourished Adults
| Autor: | Lawrence J. Cheskin, Kavita H. Poddar, Sanjivani Kolge, Tricia L. Nilles, Michelande Ridore, Eve Carlson, Andrea H. Mitola, Joseph B. Margolick, Jacob Chou, Frederick A. Menendez, Scott Kahan, Shing-Jung Wang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Gerontology
Endocrinology Diabetes and Metabolism Population nutritional supplements body-mass index Physiology lcsh:TX341-641 malnutrition Disease Immune system Medicine education lcsh:RC620-627 Original Research immune function education.field_of_study Nutrition and Dietetics business.industry medicine.disease Malnutrition lcsh:Nutritional diseases. Deficiency diseases Lean body mass Underweight medicine.symptom business Body mass index Weight gain lcsh:Nutrition. Foods and food supply Food Science |
| Zdroj: | Nutrition and Metabolic Insights, Vol 2010, Iss 3, Pp 25-35 (2010) Nutrition and Metabolic Insights, Vol 3 (2010) Nutrition and Metabolic Insights |
| ISSN: | 1178-6388 |
| Popis: | In the United States, approximately 5% of the population is malnourished or has low body weight, which can adversely affect immune function. Malnutrition is more prevalent in older adults and is often a result of energy imbalance from various causes. Dietary supplementation to promote positive energy balance can reverse malnutrition, but has not been assessed for its effect on immune parameters. This 8-week clinical feeding trial evaluated the effect of a commercially available, high-protein, high-energy formula on body weight and immune parameters in 30 adult volunteers with body-mass indices (BMI) 2. After the intervention, participants gained a mean of 3.74 lbs and increased BMI by 0.58 kg/m2. The intervention improved lean body mass and limited body fat accumulation. However, no clinically significant improvements in immune measures were observed. These results support the use of high-protein, high-energy supplements in the treatment of underweight/malnutrition. Further investigation utilizing feeding studies of longer duration, and/or studying severely malnourished individuals may be needed to detect an effect on immune parameters of weight gain promoted by nutritional supplements. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
http://www.la-press.com/effect-of-nutritional-supplements-on-immune-function-and-body-weight-i-a2032
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