Epidemiological study on foot-and-mouth disease in small ruminants: Sero-prevalence and risk factor assessment in Kenya
| Autor: | Abraham K. Sangula, Salome W. Kairu-Wanyoike, G. Muchemi, George C. Gitao, Eunice C. Chepkwony |
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| Rok vydání: | 2021 |
| Předmět: |
Male
Veterinary medicine Epidemiology medicine.medical_treatment Disease Antibodies Viral Logistic regression Animal Diseases Geographical Locations 0403 veterinary science Risk Factors Seroepidemiologic Studies Medicine and Health Sciences Prevalence Animal Management Mammals 0303 health sciences Multidisciplinary Foot-and-mouth disease Goats Eukaryota Agriculture Ruminants 04 agricultural and veterinary sciences Animal husbandry Veterinary Diseases Foot-and-Mouth Disease Virus Vertebrates Medicine Female Livestock Research Article medicine.medical_specialty 040301 veterinary sciences Science Foot and Mouth Disease Biology 03 medical and health sciences Environmental health medicine Animals Risk factor 030304 developmental biology Sheep business.industry Artificial insemination Organisms Biology and Life Sciences medicine.disease Kenya Epidemiologic Studies Cross-Sectional Studies Medical Risk Factors Foot-and-Mouth Disease Amniotes People and Places Africa Herd Veterinary Science business Zoology |
| Zdroj: | PLoS ONE, Vol 16, Iss 8 (2021) PLoS ONE PLoS ONE, Vol 16, Iss 8, p e0234286 (2021) |
| ISSN: | 1932-6203 |
| Popis: | Foot-and-mouth disease (FMD) is endemic in Kenya affecting cloven-hoofed ruminants. The epidemiology of the disease in small ruminants (SR) is not documented. We carried out a cross-sectional study, the first in Kenya, to estimate the sero-prevalence of FMD in SR and the associated risk factors nationally. Selection of animals to be sampled used a multistage cluster sampling approach. Serum samples totaling 7564 were screened for FMD antibodies of Non-Structural-Proteins using ID Screen®NSP Competition ELISA kit. Data were analysed using Statistical Package for Social Studies Version 20. To identify the risk factors, chi-square and logistic regression analyses were used. The country animal level sero-prevalence was 23.3% (95% CI: 22.3-24.3%) while herd level sero-prevalence was 77.6% (95% CI: 73.9-80.9%). Sero-positivity was significantly higher in the pastoral zone (31.5%) than in the sedentary zone at 14.5% (χ2 =303.2, pThis study showed that there is widespread undetected virus circulation in SR indicated by ubiquitous spatial distribution of significant FMD sero-positivity in the country. The risk factors were mainly husbandry related. Strengthening of risk-based FMD surveillance in carrier SR which pose potential risk of virus transmission to other susceptible species is recommended. Adjustment of husbandry practices to control FMD in SR and in-contact species is suggested. Cross-transmission and more risk factors need to be researched. |
| Databáze: | OpenAIRE |
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