Gestational Diabetes Mellitus: Using the Fasting Plasma Glucose Level to Simplify the International Association of Diabetes and Pregnancy Study Groups Diagnostic Algorithm in an Adult South Asian Population
| Autor: | Asha Sharma, John Punnose, Naimaa Choudhary, Mukesh M. Agarwal, Komal Sukhija |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Blood Glucose Study groups Asia endocrine system diseases Endocrinology Diabetes and Metabolism Population South asian population 030209 endocrinology & metabolism 030204 cardiovascular system & hematology Sensitivity and Specificity Plasma glucose level 03 medical and health sciences Young Adult 0302 clinical medicine Endocrinology Asian People Predictive Value of Tests Pregnancy Diabetes mellitus Prenatal Diagnosis Internal Medicine Medicine Humans Mass Screening education Societies Medical education.field_of_study Receiver operating characteristic business.industry nutritional and metabolic diseases International Agencies General Medicine Fasting Glucose Tolerance Test medicine.disease Gestational diabetes Diabetes Gestational Female business Algorithm Algorithms |
| Zdroj: | Canadian journal of diabetes. 42(5) |
| ISSN: | 2352-3840 |
| Popis: | To evaluate the value of the fasting plasma glucose (FPG) level for simplifying the International Association of Diabetes and Pregnancy Study Groups (IADPSG) diagnostic algorithm of gestational diabetes mellitus (GDM) in a South Asian population.In 6,520 pregnant women undergoing universal screening with the 75 g oral glucose tolerance test (OGTT), the area under receiver operating characteristic curve was used to determine the overall FPG performance to detect GDM (IADPSG criteria). Specifically, 2 different FPG thresholds of the OGTT were used to rule in and rule out GDM so as to decrease the need for the cumbersome OGTT.GDM was present in 1,193 (18.3%) women. The FPG 1) area under receiver operating characteristic curve (95% CI) was 0.909 (0.898 to 0.920); 2) threshold of ≥5.1 mmol/L independently could rule in GDM in 708 (10.9%) women (100% specificity); 3) threshold of4.3 mmol/L independently could rule out GDM in an additional 2,389 (36.6%) women (95.6% sensitivity).By circumventing nearly one half the OGTTs, an initial FPG can simplify the onerous GDM diagnostic IADPSG algorithm in this population parochially and in countries with large South Asian immigrant populations-without compromising medical care. |
| Databáze: | OpenAIRE |
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