Clinical manifestations in children with tonsillar lymphoma: A systematic review
| Autor: | Lucas Ricci Bento, Alexandre Caixeta Guimarães, Reinaldo Jordão Gusmão, Carlos Roberto Silveira Corrêa, Guilherme Machado de Carvalho |
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| Rok vydání: | 2014 |
| Předmět: |
Pathology
medicine.medical_specialty Lymphoma Tonsillar Neoplasms MEDLINE Palatine tonsil Tonsillar Neoplasm stomatognathic system immune system diseases Cervical lymphadenopathy hemic and lymphatic diseases otorhinolaryngologic diseases medicine Humans Child business.industry Hematology respiratory system medicine.disease Dermatology medicine.anatomical_structure Oncology B symptoms Tonsil Tonsillar Lymphoma medicine.symptom business |
| Zdroj: | Critical Reviews in Oncology/Hematology. 90:146-151 |
| ISSN: | 1040-8428 |
| DOI: | 10.1016/j.critrevonc.2013.12.005 |
| Popis: | Background The lymphoma is the most common childhood malignancy in the head and neck. Approximately 15% of head and neck lymphomas in children affect the Waldeyer's ring. Early diagnosis and treatment are of great importance in the prognosis of tonsillar lymphoma patients. Objectives To realize a systematic review of the literature on the clinical manifestations present at diagnosis of tonsillar lymphoma in pediatric patients. Date Source Articles in English, Spanish or Portuguese in the last 15 years about lymphoma in palatine tonsil in children from PubMed/Medline, LILACS, IBECS, Cochrane, SCIELO, BIREME and Scopus. Study eligibility criteria It was included articles and case reports that covered the pediatric age group, up to 18 years old and that contained information of the clinical manifestations of tonsillar lymphoma at diagnosis. Results We found 87 articles of which 18 were included; there were 66 cases of lymphoma of palatine tonsils. The most common clinical manifestations found in children with lymphoma in palatine tonsils were unilateral tonsillar enlargement (72.7%), alteration in appearance of the tonsil (45.4%) and cervical lymphadenopathy (30.3%). The presence of B symptoms occurred in only 16% of the patients. Burkitt was the most common type of lymphoma found. Conclusion The most common clinical manifestations of lymphoma in palatine tonsil are the tonsils asymmetry, alteration in the appearance of the mucous and cervical lymphadenopathy. A detailed description of cases of lymphoma in palatine tonsils and the use of criteria for classification of tonsillar asymmetry are important for future revisions. |
| Databáze: | OpenAIRE |
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