Elemental analysis and clinical implications of calcification deposits associated with silicone breast implants
| Autor: | D S Raso, Luke Jl, Young Vl, Maureen A. Riopel, William B. Greene, Askin Fb, J F Silverman, Kalasinsky Vf |
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| Rok vydání: | 1999 |
| Předmět: |
Calcium Phosphates
medicine.medical_specialty Pathology Spectrophotometry Infrared Breast Implants Silicone Gels chemistry.chemical_compound Breast Diseases Silicone Breast cancer Calcinosis medicine Mammography Humans Breast skin and connective tissue diseases medicine.diagnostic_test business.industry technology industry and agriculture Capsule Middle Aged medicine.disease stomatognathic diseases chemistry Microscopy Electron Scanning Surgery Female Radiology Implant business Calcification Electron Probe Microanalysis |
| Zdroj: | Annals of plastic surgery. 42(2) |
| ISSN: | 0148-7043 |
| Popis: | Calcification of the fibrous capsule surrounding silicone breast implants is a well-recognized occurrence that increases with time following implantation. These mineralized deposits potentially confound mammographic breast cancer surveillance already made difficult by the obscuring effects of silicone breast implants. The authors performed elemental analysis of silicone breast implant-associated calcifications to define better their chemical composition as related to mammographic and clinical significance. Electron probe microanalysis and infrared spectroscopy revealed all of the calcification deposits to be calcium complexed with tribasic phosphate. No evidence of calcium oxalate, calcium carbonate, silicone, or talc was observed. Caution must be employed in interpreting mammograms in women with silicone breast implants as well as those who have had their silicone breast implants removed. High-density mammographic calcifications indicative of calcium phosphate associated with a silicone breast implant may represent an accepted consequence of implantation or nearby carcinoma. We recommend baseline mammography on women who have had their silicone breast implants removed to prevent unnecessary fine-needle aspiration or tissue biopsy of retained breast capsule calcifications during subsequent routine surveillance for carcinoma. |
| Databáze: | OpenAIRE |
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