Evaluation of the sexual health in people living with hemophilia

Autor:	Jeffrey S. Stonebraker, Mark Crowther, Randall Curtis, Declan Noone, Michael B. Nichol, Federico Germini, Brian O'Mahony, Mark W. Skinner, Drashti Pete, David Page, Chatree Chai-Adisaksopha, Neil Frick, Lehana Thabane, Alfonso Iorio
Rok vydání:	2021
Předmět:	Adult Pediatrics medicine.medical_specialty Adolescent Hemophilia A Hemophilia B Odds Hemarthrosis Humans Medicine Range of Motion Articular Genetics (clinical) Health policy Aged Reproductive health business.industry Chronic pain Hematology General Medicine Odds ratio medicine.disease Confidence interval Patient-reported outcome Sexual Health Range of motion business
Zdroj:	Haemophilia. 27:993-1001
ISSN:	1365-2516 1351-8216
Popis:	Background Knowledge about sexual health, difficulty with sexual activity and intimacy (sexual difficulty), in people with hemophilia is little understood. Objectives The objectives were to determine the prevalence of sexual difficulty in people living with hemophilia (PWH) compared to people with no bleeding disorders (PWNoBD), and to determine factors associated with it. Methods This was an analysis of the PROBE study. We recruited individuals who had hemophilia A or B (PWH) and PWNoBD who were 18 years old or older. We calculated proportions of participants with sexual difficulty and odds ratios (ORs) adjusted for sex and age with 95% confidence intervals. Results There were 2007 PWH and 1972 PWNoBD. Mean (standard deviation) age was 41 (15) years in PWH and 42 (13) years in PWNoBD. Sexual difficulty was reported in 302 (15.1%) PWH and 79 (4.0%) PWNoBD. The odds of sexual difficulty were significantly higher in PWH (OR 3.82, 95% CI 2.85, 5.11). Among PWH, older age, experiencing acute or chronic pain in the past 12 months, bleeds within the past two weeks, ≥3 spontaneous joint bleeds (past six months), limitation of range of motion of any joints, and any life- or limb-threatening bleeds in the past 12 months were associated with sexual difficulty. Conclusions Sexual difficulty is more prevalent in people living with hemophilia and associated with markers of disease severity. Sexual health issues should be incorporated in comprehensive hemophilia care, future research, and hemophilia related health policy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3f2e6f834d27ce13fede9216fe0886 https://doi.org/10.1111/hae.14410 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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