Spray-Dried Yerba Mate Extract Capsules: Clinical Evaluation and Antioxidant Potential in Healthy Individuals
| Autor: | Antônio Corrêa Lindenberg, Fernanda de Andrade, Edson Luiz da Silva, Tales de Carvalho, Heloisa Pamplona Cunha, Aline Minuzzi Becker, Brunna Cristina Bremer Boaventura |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Antioxidant Thiobarbituric acid medicine.medical_treatment Capsules medicine.disease_cause Thiobarbituric Acid Reactive Substances Antioxidants Superoxide dismutase Lipid peroxidation 03 medical and health sciences chemistry.chemical_compound 0404 agricultural biotechnology food Ilex paraguariensis Yerba-mate medicine Humans Ingestion Food science 030109 nutrition & dietetics biology Plant Extracts 04 agricultural and veterinary sciences Glutathione Catalase 040401 food science food.food chemistry Chemistry (miscellaneous) biology.protein Oxidative stress Food Science |
| Zdroj: | Plant Foods for Human Nutrition. 74:495-500 |
| ISSN: | 1573-9104 0921-9668 |
| DOI: | 10.1007/s11130-019-00764-4 |
| Popis: | The aim of the present study was to evaluate the clinical effects and antioxidant potential of spray-dried yerba mate extract (SDME) capsules in healthy individuals. Fourteen healthy volunteers consumed three capsules of SDME three times daily. Measurements were carried out at the baseline and after 7, 30, and 60 days of SDME capsules intake. Electrocardiogram, hematological, urinary, and biochemical parameters analyzed remained within the normal values during all the study. SDME capsules ingestion increased significantly serum antioxidant capacity (after 7 and 30 days) and reduced glutathione values (after 7 and 60 days), and the superoxide dismutase (after 7, 30, and 60 days), catalase (after 7 and 30 days), and paraoxonase-1 activities (after 7 days); and decreased lipid hydroperoxides (after 30 and 60 days) and thiobarbituric acid reactive substances levels (after 7 and 30 days). No change was observed for glutathione peroxidase activity after SDME capsules intake. The present study showed that SDME capsules ingestion by healthy individuals did not promote clinical changes and promoted an increase of antioxidant biomarkers with a concomitant decrease of lipid peroxidation biomarkers in a short and prolonged manner. |
| Databáze: | OpenAIRE |
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