Calcium and cGMP in Isolated Rat Parotid Acinar Cells
| Autor: | J.A. Mangos, W. Farnham, R.L. Boyd, D. Bouchlas |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
0301 basic medicine
GUCY1B3 medicine.medical_specialty Biological Transport Active chemistry.chemical_element Calcium 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Animals Parotid Gland Receptors Cholinergic Cyclic GMP General Dentistry GUCY1A3 Muscarinic acetylcholine receptor M3 Muscarinic acetylcholine receptor M2 030206 dentistry Guanylate cyclase 2C Muscarinic acetylcholine receptor M1 NPR1 Receptors Muscarinic Acetylcholine Rats Cell biology 030104 developmental biology Endocrinology chemistry Potassium |
| Zdroj: | Journal of Dental Research. 59:1442-1446 |
| ISSN: | 1544-0591 0022-0345 |
| DOI: | 10.1177/00220345800590081401 |
| Popis: | The role of calcium ions in the activation of guanylate cyclase and in the propagation of the effects of cGMP during activation of the muscarinic cholinergic receptors was studied in isolated rat parotid acinar cells. It was demonstrated that the requirement for extracellular calcium is complete in the transduction of information from the muscarinic receptor to the guanylate cyclase, and partial in the steps beyond the synthesis of cGMP. |
| Databáze: | OpenAIRE |
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