Cytological diagnosis of juvenile xanthogranuloma: A rare histiocytic disorder
| Autor: | Aakanksha Singh, Shivangi Chauhan, Preeti Diwaker, Vinod Kumar Arora, Priyanka Gogoi |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Histology Juvenile xanthogranuloma Biopsy Fine-Needle 030209 endocrinology & metabolism Pathology and Forensic Medicine 03 medical and health sciences 0302 clinical medicine Touton giant cell Cytology medicine Humans Head and neck Histiocyte Skin Cutaneous Mastocytosis business.industry Infant Histiocytes General Medicine medicine.disease Dermatology medicine.anatomical_structure 030220 oncology & carcinogenesis Scalp Female Histopathology business Xanthogranuloma Juvenile |
| Zdroj: | Diagnostic Cytopathology. 48:66-70 |
| ISSN: | 1097-0339 8755-1039 |
| Popis: | Juvenile xanthogranuloma (JXG) is a rare type of non-Langerhan cell histiocytic disorder, which is mostly confined to skin of head and neck. It is a self-limiting benign condition, which does not require surgery. We present a case of 8-month-old girl child with multiple yellowish brown colored papules over scalp, face, and neck. A clinical diagnosis of cutaneous mastocytosis was made. Fine-needle aspiration cytology (FNAC) smears showed foamy macrophages along with mixed inflammatory infiltrate and few touton giant cells. A diagnosis of JXG was rendered which was confirmed on histopathology and immunohistochemistry.Juvenile xanthogranuloma can be diagnosed on FNAC based on its characteristic cytologic features; however, it requires a high index of suspicion by cytopathologist. Cytological diagnosis of JXG can save the patient from unnecessary surgical biopsy or excision. |
| Databáze: | OpenAIRE |
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