Ecstasy Abuse and Its Effects on the Oral Mucosa
| Autor: | Darcy Fernandes, Rose Mara Ortega, Jorge Esquiche León, Mariel Ruivo Biancardi, Heitor Albergoni Da Silveira, Luciana Yamamoto Almeida, Andreia Bufalino |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
medicine.medical_specialty Nausea N-Methyl-3 4-methylenedioxyamphetamine medicine.medical_treatment Ecstasy Administration Oral Tongue Diseases Young Adult 03 medical and health sciences 0302 clinical medicine Facial Pain Mucositis Humans Medicine Oral mucosa Young adult 030223 otorhinolaryngology Oral Ulcer Stomatitis Illicit Drugs business.industry Mouth Mucosa 030206 dentistry General Medicine medicine.disease Dermatology Stimulant stomatognathic diseases medicine.anatomical_structure Otorhinolaryngology Hallucinogens Female Surgery Headaches medicine.symptom business Spongiosis |
| Zdroj: | Journal of Craniofacial Surgery. 30:e189-e191 |
| ISSN: | 1049-2275 |
| DOI: | 10.1097/scs.0000000000005033 |
| Popis: | Ecstasy is an illicit drug that has been increasingly abused by young people. This synthetic drug has both stimulant and hallucinogenic effects and is usually consumed in a tablet. The side effects of ecstasy use include nausea, muscle cramping, fever, and symptoms mostly linked to muscular tension including jaw pain, facial pain, and headaches. There are few studies assessing the ecstasy effects on the oral mucosa, both clinically and histopathologically. The authors report 2 young women (22- and 27-year-old) who presented multifocal oral erosions and ulcerations. The lesions were painful and covered by a yellow-white pseudomembrane with a bright erythematous halo. By microscopy, it was observed superficial ulceration surrounded by acanthotic squamous epithelium with marked spongiosis, interstitial edema within the corion and perivascular lyphoid infiltrate, suggesting drug-induced oral mucositis. In conclusion, ecstasy use may be associated with the development of oral ulcers, which should be considered in the differential diagnosis when assessing multifocal oral ulcerations, especially in young people. |
| Databáze: | OpenAIRE |
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