Synthesis of silver nanoparticles using flavonoids: hesperidin, naringin and diosmin, and their antibacterial effects and cytotoxicity
| Autor: | Deepika Soni, B. Chandrashekhar, Bijaya Ketan Sarangi, Nidhi Sahu, Sivanesan Saravanadevi, R.A. Pandey, Dewanand Satpute |
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| Rok vydání: | 2016 |
| Předmět: |
Materials science
Reducing agent Biomedical Engineering Diosmin Pharmaceutical Science Medicine (miscellaneous) Nanochemistry Nanoparticle Bioengineering 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Silver nanoparticle 0104 chemical sciences chemistry.chemical_compound Hesperidin chemistry medicine Organic chemistry Fourier transform infrared spectroscopy 0210 nano-technology Naringin Nuclear chemistry medicine.drug |
| Zdroj: | International Nano Letters. 6:173-181 |
| ISSN: | 2228-5326 2008-9295 |
| DOI: | 10.1007/s40089-016-0184-9 |
| Popis: | Three different flavonoids -hesperidin, naringin and diosmin (constituents of citrus plants) were used for the synthesis of silver nanoparticles (AgNPs). Aqueous solutions of pure flavonoids (0.2 mg mL−1) mixed with 1 mM AgNO3 solution were exposed to bright sunlight to prepare the nanoparticles. Characterization of the synthesized nanoparticles by UV–Visible spectrophotometer, X-ray diffraction, Fourier transform infrared spectroscopy, and transmission electron microscopy revealed that the synthesized silver nanoparticles were 10–80 nm in size and polydispersed in nature. Bactericidal effect against common pathogens and cytotoxicity of the synthesized silver nanoparticles was investigated on human promyelocytic leukemic (HL-60) cells. It is concluded that AgNPs synthesized using Naringin as reducing agent showed higher stability and better antibacterial and cytotoxic activities. |
| Databáze: | OpenAIRE |
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