Spontaneous aneuploidy and clone formation in adipose tissue stem cells during different periods of culturing
| Autor: | O. A. Buyanovskaya, N. P. Bochkov, L. D. Katosova, V. A. Nikitina, N. P. Kuleshov, E. S. Voronina |
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| Rok vydání: | 2009 |
| Předmět: |
Monosomy
Stem Cells Mesenchymal stem cell Clone (cell biology) Chromosome Adipose tissue Aneuploidy General Medicine In situ hybridization Biology medicine.disease Molecular biology General Biochemistry Genetics and Molecular Biology Clone Cells Adipose Tissue medicine Chromosomes Human Humans Stem cell Cells Cultured |
| Zdroj: | Bulletin of experimental biology and medicine. 148(1) |
| ISSN: | 1573-8221 |
| Popis: | Cytogenetic analysis of 13 mesenchymal stem cell cultures isolated from normal human adipose tissue was carried out at different stages of culturing. The incidence of chromosomes 6, 8, 11, and X aneuploidy and polyploidy was studied by fl uorescent in situ hybridization. During the early passages, monosomal cells were more often detected than trisomal ones. A clone with chromosome 6 monosomy was detected in three cultures during late passages. |
| Databáze: | OpenAIRE |
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