German ablation registry: Cryoballoon vs radiofrequency ablation in paroxysmal atrial fibrillation—One-year outcome data
Autor: | Jochen Senges, Karl-Heinz Kuck, Stephan Willems, Thomas Deneke, Dietrich Andresen, Uwe Dorwarth, Ellen Hoffmann, Martin Schmidt, Malte Kuniss, Matthias Hochadel, Jin-Hong Gerds-Li, Jürgen Tebbenjohanns, Johannes Brachmann, Stefan G. Spitzer |
---|---|
Rok vydání: | 2016 |
Předmět: |
Male
medicine.medical_specialty Radiofrequency ablation medicine.medical_treatment Catheter ablation 030204 cardiovascular system & hematology Cryosurgery Disease-Free Survival law.invention Electrocardiography 03 medical and health sciences Postoperative Complications 0302 clinical medicine Heart Conduction System Recurrence law Germany Physiology (medical) Internal medicine Atrial Fibrillation medicine Humans Prospective Studies Registries 030212 general & internal medicine Tachycardia Paroxysmal Prospective cohort study Survival rate Aged business.industry Incidence Cryoablation Atrial fibrillation Middle Aged Prognosis Ablation medicine.disease Survival Rate Treatment Outcome Catheter Ablation Cardiology Female Cardiology and Cardiovascular Medicine Energy source business Follow-Up Studies |
Zdroj: | Heart Rhythm. 13:836-844 |
ISSN: | 1547-5271 |
Popis: | Background Although radiofrequency (RF) ablation has long been the standard of care for atrial fibrillation (AF) ablation, cryoballoon technology has emerged as a feasible approach with promising results. Prospective multicenter registry data referring to both ablation technologies in AF ablation are lacking so far. Objective The purpose of this study was to report data from the German ablation registry with respect to efficacy and safety in pulmonary vein ablation with different energy sources for paroxysmal AF after 1-year follow-up. Methods A total of 2306 patients with symptomatic paroxysmal AF from the German ablation registry were included in this analysis. The cohort was divided into two groups according to the ablation energy source used: cryoballoon and RF ablation. MACCE was defined as a combination of death, myocardial infarction, or stroke. Results AF recurrence rate after a single ablation procedure at 1 year follow-up was not significantly different between the two groups (45.8% after cryoablation and 45.4% after RF ablation, P = .87). Also, the rate of patients without AF recurrence and free of antiarrhythmic drug at 12-month follow-up was similar (cryoablation 44.2% and RF 41.4%, P = .25). MACCE occurred with an incidence of 0.7% within 500 days after cryoablation and 1.4% after RF ablation ( P = .30). Persistent phrenic nerve palsy was more common after cryoablation compared to RF ablation (1.1% vs 0.3%, P Conclusion AF recurrence rate at 1-year follow-up was similar in RF ablation compared to cryoablation, whereas the spectrum and relevance of complications were significantly different between the two ablation methods. This finding might influence the choice of ablation method offered to the individual paroxysmal AF patient. |
Databáze: | OpenAIRE |
Externí odkaz: |