German ablation registry: Cryoballoon vs radiofrequency ablation in paroxysmal atrial fibrillation—One-year outcome data

Autor: Jochen Senges, Karl-Heinz Kuck, Stephan Willems, Thomas Deneke, Dietrich Andresen, Uwe Dorwarth, Ellen Hoffmann, Martin Schmidt, Malte Kuniss, Matthias Hochadel, Jin-Hong Gerds-Li, Jürgen Tebbenjohanns, Johannes Brachmann, Stefan G. Spitzer
Rok vydání: 2016
Předmět:
Male
medicine.medical_specialty
Radiofrequency ablation
medicine.medical_treatment
Catheter ablation
030204 cardiovascular system & hematology
Cryosurgery
Disease-Free Survival
law.invention
Electrocardiography
03 medical and health sciences
Postoperative Complications
0302 clinical medicine
Heart Conduction System
Recurrence
law
Germany
Physiology (medical)
Internal medicine
Atrial Fibrillation
medicine
Humans
Prospective Studies
Registries
030212 general & internal medicine
Tachycardia
Paroxysmal
Prospective cohort study
Survival rate
Aged
business.industry
Incidence
Cryoablation
Atrial fibrillation
Middle Aged
Prognosis
Ablation
medicine.disease
Survival Rate
Treatment Outcome
Catheter Ablation
Cardiology
Female
Cardiology and Cardiovascular Medicine
Energy source
business
Follow-Up Studies
Zdroj: Heart Rhythm. 13:836-844
ISSN: 1547-5271
Popis: Background Although radiofrequency (RF) ablation has long been the standard of care for atrial fibrillation (AF) ablation, cryoballoon technology has emerged as a feasible approach with promising results. Prospective multicenter registry data referring to both ablation technologies in AF ablation are lacking so far. Objective The purpose of this study was to report data from the German ablation registry with respect to efficacy and safety in pulmonary vein ablation with different energy sources for paroxysmal AF after 1-year follow-up. Methods A total of 2306 patients with symptomatic paroxysmal AF from the German ablation registry were included in this analysis. The cohort was divided into two groups according to the ablation energy source used: cryoballoon and RF ablation. MACCE was defined as a combination of death, myocardial infarction, or stroke. Results AF recurrence rate after a single ablation procedure at 1 year follow-up was not significantly different between the two groups (45.8% after cryoablation and 45.4% after RF ablation, P = .87). Also, the rate of patients without AF recurrence and free of antiarrhythmic drug at 12-month follow-up was similar (cryoablation 44.2% and RF 41.4%, P = .25). MACCE occurred with an incidence of 0.7% within 500 days after cryoablation and 1.4% after RF ablation ( P = .30). Persistent phrenic nerve palsy was more common after cryoablation compared to RF ablation (1.1% vs 0.3%, P Conclusion AF recurrence rate at 1-year follow-up was similar in RF ablation compared to cryoablation, whereas the spectrum and relevance of complications were significantly different between the two ablation methods. This finding might influence the choice of ablation method offered to the individual paroxysmal AF patient.
Databáze: OpenAIRE
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