Can umbilical artery Doppler findings at 36 weeks’ gestation predict maternal hypertension at later gestation?
| Autor: | Junichi Hasegawa, Ryu Matsuoka, Akihiko Sekizawa, Hiroko Takita, Shoko Hamada, Akihiro Kawashima, Tatsuya Arakaki, Masamitsu Nakamura |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
medicine.medical_specialty Pregnancy Trimester Third Gestational Age 030204 cardiovascular system & hematology Ultrasonography Prenatal Umbilical Arteries Preeclampsia Young Adult 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Pregnancy medicine.artery Humans Maternal hypertension Medicine Prospective Studies Prospective cohort study Gynecology 030219 obstetrics & reproductive medicine business.industry Obstetrics Infant Newborn Obstetrics and Gynecology Gestational age Umbilical artery Hypertension Pregnancy-Induced Middle Aged medicine.disease Blood pressure ROC Curve Ultrasonography Doppler Pulsed Case-Control Studies Pediatrics Perinatology and Child Health Gestation Female business |
| Zdroj: | The Journal of Maternal-Fetal & Neonatal Medicine. 30:177-180 |
| ISSN: | 1476-4954 1476-7058 |
| Popis: | To clarify whether ultrasonographic evaluations of fetoplacental underperfusion using umbilical artery (UmA) Doppler indices at 36 weeks' gestation can predict maternal hypertension at later gestation.Normotensive pregnant women who underwent an ultrasound scan at 36 weeks' gestation and delivered singleton infants at term between 2012 and 2013 were prospectively enrolled. UmA Doppler and maternal blood pressure results at 36 weeks' gestation in cases with pregnancy-induced hypertension (PIH) at later gestation were compared with a control group.Thirty-nine and 775 cases were classified into the PIH and control group, respectively. The UmA pulsatility index (PI) and maternal systolic blood pressure (SBP) at 36 weeks' gestation were higher in the PIH group than in control group (UmA-PI: 0.88 vs. 0.80, p = 0.002; SBP: 126 mmHg vs. 112 mmHg, p 0.001). The area under the ROC curve for the prediction of PIH by combining the UmA-PI and SBP was 0.867 (95% confidence interval (CI): 0.781, 0.954). The detection rate for PIH was 64.0% with a 10% false-positive rate.An increased UmA-PI at 36 weeks' gestation is associated with the occurrence of PIH at later gestation. This result may indicate the possibility to detect fetoplacental underperfusion ultrasonically. |
| Databáze: | OpenAIRE |
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