| Autor: |
Elisa Estenssoro, Cecilia I. Loudet, Arnaldo Dubin, Vanina S. Kanoore Edul, Gustavo Plotnikow, Macarena Andrian, Ignacio Romero, Judith Sagardía, Marco Bezzi, Verónica Mandich, Carla Groer, Sebastián Torres, Cristina Orlandi, Paolo N. Rubatto Birri, María F. Valenti, Eleonora Cunto, María G. Sáenz, Norberto Tiribelli, Vanina Aphalo, Lisandro Bettini, Fernando G. Ríos, Rosa Reina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Journal of Critical Care. 71:154021 |
| ISSN: |
0883-9441 |
| Popis: |
To identify determinants of oxygenation over time in patients with COVID-19 acute respiratory distress syndrome (ARDS); and to analyze their characteristics according to Berlin definition categories.Prospective cohort study including consecutive mechanically ventilated patients admitted between 3/20/2020-10/31/2020 with ARDS. Epidemiological and clinical data on admission; outcomes; ventilation, respiratory mechanics and oxygenation variables were registered on days 1, 3 and 7 for the entire population and for ARDS categories.1525 patients aged 61 ± 13, 69% male, met ARDS criteria; most frequent comorbidities were obesity, hypertension, diabetes and respiratory disease. On admission, 331(21%), 849(56%) and 345(23%) patients had mild, moderate and severe ARDS; all received lung-protective ventilation (mean tidal volumes between 6.3 and 6.7 mL/kg PBW) and intermediate PEEP levels (10-11 cmHHypoxemia in patients with COVID-19-related ARDS is associated with comorbidities, deadspace and activated coagulation markers, and disease severity-reflected by the PEEP level required. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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