Airway Clearance and Mucoactive Therapies
| Autor: | Gerard Muñoz Castro, Ana Balañá Corberó |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pulmonary and Respiratory Medicine
Airway clearance Respiratory Therapy Bronchiectasis business.industry Mucociliary clearance Mucin Respiratory System Critical Care and Intensive Care Medicine medicine.disease Mucus 03 medical and health sciences 0302 clinical medicine 030228 respiratory system Mucociliary Clearance Immunology Medicine Humans 030212 general & internal medicine Respiratory system Respiratory physiotherapy business Airway |
| Zdroj: | Seminars in respiratory and critical care medicine. 42(4) |
| ISSN: | 1098-9048 |
| Popis: | The respiratory system is constantly exposed to external pathogens but has different and effective defense systems. The pathophysiology of bronchiectasis affects the defense system considerably in that alterations occur in the airway that reduce its effectiveness in mucociliary clearance and the greater presence of mucins leads to the accumulation of more adherent and viscous mucus. One of the pillars of treatment of this disease should be improvement of mucociliary clearance and a decrease in the adherence and viscosity of the mucus. To this end, the mobilization of secretions must be increased through effective respiratory physiotherapy techniques, which can be manual and/or instrumental. The properties of mucus can be modified to improve its mobilization through the use of a mucoactive agent. Despite the increase in the number and quality of studies, the evidence for these treatments remains scarce, although their application is recommended in all guidelines. |
| Databáze: | OpenAIRE |
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