NMR spectroscopy using Rabi modulated continuous wave excitation
| Autor: | James C. Korte, Leigh A. Johnston, Kelvin J. Layton, Peter M. Farrell, Bahman Tahayori, Stephen Moore |
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| Přispěvatelé: | Korte, James C, Layton, Kelvin J, Tahayori, Bahman, Farrell, Peter M, Moore, Stephen M, Johnston, Leigh A |
| Rok vydání: | 2017 |
| Předmět: |
spectroscopy
Rabi cycle Health Informatics Spectral line 030218 nuclear medicine & medical imaging 03 medical and health sciences symbols.namesake 0302 clinical medicine nonlinear system modelling Physics Condensed matter physics amplitude modulation Relaxation (NMR) Resonance NMR optimal experimental design Fourier transform Bloch equations Signal Processing continuous wave excitation symbols inverse problem Continuous wave bloch equations Atomic physics 030217 neurology & neurosurgery Excitation |
| Zdroj: | Biomedical Signal Processing and Control. 33:422-428 |
| ISSN: | 1746-8094 |
| DOI: | 10.1016/j.bspc.2016.10.006 |
| Popis: | We present a proof of principle method to reconstruct nuclear magnetic resonance spectra after perturbing the spin system with a series of Rabi modulated continuous wave excitations. This continuous wave method provides an exciting alternative to pulsed Fourier transform methods which dominate magnetic resonance techniques. Applications include the measurement of ultra-short relaxation samples, which would be beneficial for sodium imaging or the assessment of bone and connective tissues. It is known that under Rabi modulated continuous wave excitation the spin system will reach a substantial periodic orbit. In a first experiment, we confirm that these periodic orbits are affected by off-resonance effects, and therefore encode chemical shift information. Spectroscopy is posed as an inverse problem in a second experiment and we apply a nonlinear estimation model to obtain nuclear magnetic resonance spectra from experimental measurements. Refereed/Peer-reviewed |
| Databáze: | OpenAIRE |
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