Cystic fibrosis associated liver disease in children
| Autor: | Girish L Gupte, Joseph J Valamparampil |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Liver transplantation Hepatology Distal intestinal obstructive syndrome business.industry Minireviews medicine.disease Gastroenterology Cystic fibrosis Cystic fibrosis liver disease Cystic fibrosis transmembrane conductance regulator modulators Liver disease Cirrhosis Internal medicine Medicine business Portal hypertension |
| Zdroj: | World Journal of Hepatology |
| ISSN: | 1948-5182 |
| Popis: | Cystic fibrosis (CF) is an autosomal recessive disorder caused by mutations in the CF transmembrane conductance regulator gene. CF liver disease develops in 5%-10% of patients with CF and is the third leading cause of death among patients with CF after pulmonary disease or lung transplant complications. We review the pathogenesis, clinical presentations, complications, diagnostic evaluation, effect of medical therapies especially CF transmembrane conductance regulator modulators and liver transplantation in CF associated liver disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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