Is Serum Methylmalonic Acid a Reliable Biomarker of Vitamin B12 Status in Children with Short Bowel Syndrome: A Case Series

Autor:	Danielle A. Stamm, Brittany Depaula, Lissette Jimenez, Christopher Duggan
Rok vydání:	2018
Předmět:	Male Short Bowel Syndrome medicine.medical_specialty Methylmalonic acid Gastroenterology Article Diagnosis Differential Elevated serum 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine 030225 pediatrics Internal medicine medicine Humans Vitamin B12 Child business.industry food and beverages Vitamin B 12 Deficiency Short bowel syndrome medicine.disease digestive system diseases Vitamin B 12 Endocrinology chemistry Child Preschool Vitamin B Complex Pediatrics Perinatology and Child Health Biomarker (medicine) Female 030211 gastroenterology & hepatology SMALL BOWEL BACTERIAL OVERGROWTH Blind Loop Syndrome business Biomarkers Methylmalonic Acid
Zdroj:	The Journal of Pediatrics. 192:259-261
ISSN:	0022-3476
DOI:	10.1016/j.jpeds.2017.09.024
Popis:	We describe 3 patients with short bowel syndrome who had persistently elevated serum methylmalonic acid (MMA) levels while being treated for vitamin B12 deficiency. Following treatment for presumed small bowel bacterial overgrowth, MMA levels normalized. Among patients with short bowel syndrome, MMA levels may have limited specificity for vitamin B12 deficiency.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b0d5245d4bf22a269b78f9281c19332 https://doi.org/10.1016/j.jpeds.2017.09.024 Zobrazit plný text záznamu Full Text from ScienceDirect