McDonald versus Shirodkar cerclage technique in women requiring a prophylactic cerclage: a systematic review and meta-analysis protocol

Autor: Kimberley P. Williams, Carol A. Wang, Ashad Issah, Anne-Marie Aubin, Jason Phung, Liam McAuliffe, Craig E. Pennell, Rosanna Diacci, Panos Maouris
Rok vydání: 2021
Předmět:
Zdroj: Systematic Reviews, Vol 10, Iss 1, Pp 1-8 (2021)
Systematic Reviews
ISSN: 2046-4053
Popis: BackgroundPreterm birth (PTB) is the leading cause of death in children under five years. Spontaneous preterm birth (SPTB) is the major cause of preterm delivery. The key risk factors for SPTB are women who have a short cervix and women who have had previous preterm birth. Cervical cerclage has been used for several decades and has shown to decrease rates of preterm birth. The most commonly used cerclage techniques were described by Shirodkar and McDonald, with no current consensus on the preferred technique. The objective of this review is to determine and compare the effectiveness of both techniques.MethodsStudies will be sourced from six electronic databases, as well as from experts in the field, reference lists, and grey literature. Eligible studies will include pregnant women, with a singleton or twin pregnancy, requiring a cervical cerclage, using either the Shirodkar or McDonald technique and run comparative analyses between the two techniques. Randomized control trials (RCT)s, non-randomized control trials, and cohort studies will be eligible. Two independent reviewers will conduct study screening at abstract and full-text level, data extraction and risk of bias assessment. Discrepancies will be resolved by a consensus third reviewer if required. Fixed-effects or random-effects models will be used where appropriate to synthesize results. Alternative synthesis methods will be investigated in instances where a meta-analysis is not appropriate, such as summarizing effect estimates, combiningPvalues, vote counting based on direction of effect, or synthesis in narrative form.DiscussionThis review will synthesize the evidence on both the Shirodkar and McDonald cerclage method, and will help clinicians and health services to determine and deliver best practice antenatal care that has the potential to make an impact on preterm birth.Systematic review registrationPROSPERO on 25 of May, 2020 with registration numberCRD42020177386
Databáze: OpenAIRE