Recurrent longitudinally extensive transversal myelitis in a patient with Sjögren’s syndrome
| Autor: | Zeljko Zivanovic, Aleksandra Lucic-Prokin, Kosta Petrovic, Timea Kokai-Zekic, Zita Jovin, Ivan Turkalj, Jelena Sekaric, Slobodan Gvozdenovic |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Pathology
medicine.medical_specialty diagnosis Myelitis neuromyelitis optica Transverse myelitis myelitis transverse Lumbar Adrenal Cortex Hormones Recurrence medicine Humans Sjorgen’s syndrome Pharmacology (medical) Pleocytosis lcsh:R5-920 Neuromyelitis optica medicine.diagnostic_test business.industry Lumbar puncture Hypoesthesia Middle Aged medicine.disease Spinal cord Magnetic Resonance Imaging drug therapy Sjogren's Syndrome medicine.anatomical_structure Spinal Cord treatment outcome Female medicine.symptom business lcsh:Medicine (General) |
| Zdroj: | Vojnosanitetski Pregled, Vol 70, Iss 11, Pp 1056-1058 (2013) |
| ISSN: | 0042-8450 |
| Popis: | Introduction. Longitudinally extensive transverse myelitis (LETM) is a transversal myelitis that extends through three or more vertebral segments in length. Case report. A 52- year-old woman was hospitalized due to pain in the lumbar region, difficulty in walking, hypoesthesia of the anogenital area and urinary retention. In the past medical history, two years earlier, the patient had been diagnosed with transversal myelitis confirmed by MRI of the cervical spine and six months earlier, the patient was diagnosed with primary Sj?gren?s syndrome (SS). During the current hospitalization MRI of the spinal cord revealed extensive inflammatory lesions of almost the whole spinal cord. Lumbar puncture (LP) revealed mild pleocytosis and slightly increased protein level. Isoelectric focusing of cerebrospinal fluid (CSF) and serum proteins was normal. Visual evoked potentials were normal. Serological testing excluded acute viral infections. Corticosteroid therapy was applied with good therapeutic response. Control MRI revealed regression of pathological changes in the spinal cord. Conclusion. A wide range of disorders can cause LETM, but usually the first line diagnosis is neuromyelitis optica (NMO). Based on the detection of NMO immunoglobulin G in the serum of affected patients, a variety of allied disorders were grouped under the name of NMO spectrum disorders, including recurrent myelitis associated with LETM and myelitis associated with autoimmune disorders such as SS. There have been only a few cases reported in the literature with recurrent LETM associated with non-organ specific autoimmune disorder. |
| Databáze: | OpenAIRE |
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