A case of gait disturbance caused by low-dose gabapentin
| Autor: | Osamu Takahata, Takayuki Kunisawa, Hirotsugu Kanda, Megumi Kanao-Kanda |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Side effect Gabapentin side effect gabapentin Case Report 03 medical and health sciences 0302 clinical medicine medicine Pharmacology (medical) 030212 general & internal medicine General Pharmacology Toxicology and Pharmaceutics neuropathic pain Chemical Health and Safety business.industry Gait Disturbance Low dose Brain Contusion General Medicine Surgery Anticonvulsant Agent Anesthesia Neuropathic pain gait disturbance Flunitrazepam business Safety Research 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Therapeutics and Clinical Risk Management |
| ISSN: | 1178-203X 1176-6336 |
| Popis: | Gabapentin, an anticonvulsant agent, is now often used for the treatment of neuropathic pain all over the world. It is unclear whether the combined use of gabapentin, sodium valproate, and flunitrazepam results in enhancement of the side effect, a gait disturbance. A 60-year-old man was taking oral sodium valproate for symptomatic epilepsy after a brain contusion and flunitrazepam to relieve insomnia. Oral gabapentin therapy was started for suspected neuropathic pain. Although the initial dose of oral gabapentin (200 mg) relieved the pain, the lower extremities became weak, resulting in a gait disturbance. The therapy was restarted with a halved dose, and this resolved the gait disturbance and relieved the pain. |
| Databáze: | OpenAIRE |
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